PreTest Biochemistry and Genetics is a valuable resource for students in their board preparation. The author does a good job of presenting complicated information in an easily accessible format with clinically relevant questions and detailed basic science answers？

500 USMLE-type questions and answers Detailed explanations for correct and incorrect answers Targets what you really need to know for exam success Student tested and reviewed Great for course review and the USMLE Step 1!Biochemistry and Genetics：PreTest asksthe right questions so youll know the rightanswers.Open it and start learning what’s on the test.

    The new edition of Biochemistry and Genetis PreTest： Self-Assessment and Review is based in part on earlier editions prepared by Golder N. Wilson，MD， PhD， Department of Pediatrics， Texas Tech University Health SciencesCenter; Cheryl Ingram-Smith， PhD; Kerry S. Smith， PhD， Department ofGenetics， Biochemistry， and Life Science Studies Clemson University Clemson，South Carolina; and by Francis J. Chlapowski， PhD， Department of Biochem-istry and Molecular Biology， University of Massachusetts Medical School. Allquestions are in single-best-answer format and a large number are analogousto those of the United States Medical Licensing Examination （USMLE）， Step 1.Questions are updated to the most current editions of leading textbooks in medical biochemistry and medical genetics.

Preface
Introduction
Note Concerning Disease Examples
Abbreviations
High-Yield Facts
High-Yield Facts in Biochemistry and Genetics
DNA Structure， Replication， and Repair
Questions
Answers
Gene Expression and Regulation
Questions
Answers
Acid-Base Equilibria， Amino Acids，
and Protein Structure
Questions
Answers
Protein Structure/Function
Questions
Answers
Carbohydrate Metabolism
Questions
Answers
Bioenergetics and Energy Metabolism
Questions
Answers
Lipid， Amino Acid， and Nucleotide Metabolism
Questions
Answers
Vitamins and Minerals
Questions
Answers
Hormones and Integrated Metabolism
Questions
Answers
Inheritance Mechanisms/Risk Calculations
Questions
Answers
Genetic and Biochemical Diagnosis
Questions
Answers
Appendix
Bibliography
Index

    The tetrameric structure of hemoglobin allows cooperative binding 0foxygen in that binding of oxygen to the heme molecule of the first subunitfacilitates binding to the other three.This enhanced binding is due toallosteric changes of the hemoglobin molecule,accounting for its s-shapedoxygen-saturation curve as compared with that of myoglobin（see Fig.8 0fthe High，Yield Facts）.At the lower oxygen saturations in peripheral tissues（Po,30－40）.hemoglobin releases much more oxygen（up to 50％desatu－rated）than myoglobin with its single polypeptide structure.